Kristen Hill

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In twenty years of treating bones in Stockholm, I never once wrote the prescription American doctors reach for first. And the women I treat are not the ones breaking a hip reaching for soup. I am a bone specialist from Sweden, and I cannot understand why American women are still being handed Fosamax and Prolia when the fix is this much simpler. And if you have a prescription for osteoporosis or osteopenia you have not filled yet, please read this before you do. My name is Dr. Ingrid Lindqvist. I am a bone metabolism specialist with twenty two years of experience and I have treated several thousand women with osteoporosis and osteopenia in Stockholm and across Europe. Here is what I kept running into when American women started finding their way to me. Every one of them arrived with the same number on a page, and the same relief in their voice when a doctor had told them it was good news. Stable. Holding. No further loss. Then they would tell me what happened next. A wrist that broke reaching into a cupboard. A jaw that would not heal after a tooth was pulled. A thigh bone that snapped while she was simply walking across a car park. And the one I still think about. A hip that gave way before she hit the floor, not after. And every one of them asked me the same four questions. Why did nobody tell me I could still fracture on this. Why did nobody tell me how hard it is to come off. Why did nobody read me the side effects before I started. Why did nobody tell me this drug does not build any new bone. And I sat there, a doctor trained on the other side of an ocean, realising that nobody had asked them the one question we ask first. Why are the bones thinning in the first place. Because a broken hip after fifty is not a joint that breaks. One in three women who fracture a hip are dead within the year. Half of those who live never get their independence back. Which means somebody else does her shopping, and somebody else decides where she lives. In my country we do not treat that as something to hold steady and wait out. We treat it as something to turn around. So let me explain what I kept telling these women, because almost none of them had heard it once. Bone loss is not bad luck and it is not simply age. It is a crew that was switched off years ago and never switched back on. Here is how it actually works. Inside your bone marrow there are stem cells. They have two jobs. They can become bone cells, or they can become fat cells. When you are young, they build bone, and plenty of it. Your bones stay dense and you never think about them once. But after menopause something shifts. Those same stem cells stop making bone cells. They only make fat cells. Your bone density drops. And nobody tells you it is happening, because you cannot feel a thing until something breaks. Now here is the part your doctor almost certainly never explained. There is a switch inside those stem cells. A protein called SIRT1. When SIRT1 is active, the stem cells become bone builders. When SIRT1 goes quiet, those same cells become fat. And SIRT1 runs on a single fuel. A molecule called NMN. When you are young your body makes plenty of it. The switch stays on. The builders keep building. But by forty that fuel has fallen off a cliff. By fifty there is almost none left. The switch sits there, quiet, and your stem cells quietly give up on bone and turn to fat instead. The cells never left you. They turn up every day of your life. They have simply been told to do the wrong job, because the thing that tells them to build bone ran out of fuel years ago. And this is the part I had to say out loud in my office over and over. That is exactly why the calcium did nothing. That is why the D3 did nothing. The K2. The collagen. The AlgaeCal. None of those can build a bone cell. None of those can flip the switch. They are the material. They are not the crew, and they are not the thing that turns the crew on. So I started asking the question my American patients had never been asked. What puts the fuel back inside the cell and flips that switch back on. Because the drug was never designed to. And the answer was not hidden in some wellness blog. It was sitting in the research, where it has been for years. When those stem cells got that fuel back, the switch came back on, and they started building bone again. Not losing it more slowly. Building. The first women who read this to me could not believe it, because in America the only word anyone had ever used about their bones was holding. So my first thought was the obvious one. If the fuel is gone, put the fuel back. And here is where most supplements fail before they begin. It is not what you take. It is whether it reaches the cell. NAD plus is the fuel the body actually uses. But the molecule is too large. Your gut takes it apart long before it ever reaches a bone. What does get through is the smaller piece your body uses to make it. That piece is NMN. NMN is about half the size, small enough to cross the gut lining intact. Once it is inside the cell, your body makes the fuel right there, where the switch is standing. But the research was clear that feeding the switch is only one of four jobs. And if the other three are not done, the switch still will not hold. First. NMN alone gives SIRT1 the fuel to turn back on and send the stem cells back to building bone. Second. Keeping that fuel converting cleanly costs the body something, and when it runs low the whole process stalls halfway. TMG is what keeps it topped up so the switch never goes dark again. Third. The marrow itself gets inflamed and crowded as you age, and that inflammation accelerates the loss and buries the stem cells. Quercetin clears it out so the builders have room to work. Fourth. Trans-resveratrol activates SIRT1 directly, pressing on the same switch from the other side, lifting bone mineral density and slowing the loss while the NMN gets the fuel flowing. Four jobs. Flip the switch. Keep it on. Clear the inflammation. Press the switch directly so it holds. So I went looking for something that did all four, at the amounts the research actually used. And I was genuinely surprised at what I found on the American market. NMN on its own. NMN on its own. More NMN on its own. Underdosed. Half the time it was a token amount sprinkled in so the word could go on the label. There was nothing with all four in it at the right doses. So for a long time I told women to buy four separate bottles and take them together, as long as every one hit the amount in the studies. And then I did the only thing that would tell me how well this really worked. I thought of Diane. Diane is sixty three. Six years since her diagnosis, and she had refused the drug from the very first appointment. I am glad now that she did. Her hip was at negative 2.9. She had tried everything. Calcium, D3, K2, collagen, AlgaeCal, the weighted vest, the walking, the resistance work. Name it and she had done it, and her number had gone down at every single scan. She had hiked with her daughter every other Sunday for eleven years. She stopped the year she was diagnosed. She had stopped reaching the top shelf in her own kitchen. And she had a husband who had watched her get slower for six years and had never once said so out loud. So I explained the stem cells to her, and the switch, and the fuel that had run dry years before anyone scanned her. And I told her to go and read it herself before she bought a thing. Because I was not going to hand her something and send her off the way her American doctors had. She rang me a week later having read more of it than I had. She bought all four separately. Four bottles, eight capsules a day. And she kept every single thing she was already taking. The calcium, the D3, the K2, all of it. She stopped nothing. She simply added the one thing nobody had ever touched. The switch. Month one, nothing. She rang me worried. I told her that was the correct answer, because there is nothing to feel yet. Bone does not announce itself. Month two was her afternoons. She stopped reaching for the second coffee at two o'clock. I told her why. Every cell in the body runs on that same fuel, and hers had been low for years. It meant it was getting in. It meant nothing yet about her hip. Month three she went hiking with her daughter. First Sunday in six years. Month four she got the shelf. She reached up for a bowl without doing the calculation first, and had it in her hand before she realised what she had just done. Month five her husband told her she was moving like she used to. She had not said a word to him about any of it. And somewhere in the middle of all that, the fear went. She could not tell me which week. She just stopped moving around her own house like a woman waiting for something to give way. I told her what I tell everybody. You cannot feel bone. But when a woman starts feeling like that, it is time to scan her. So at six months I sent her for one. Negative 2.4. Up from negative 2.9. Out of the osteoporosis range, after six years of watching it only ever go the other way. Then she asked me the question her doctors should have answered six years earlier. Why had none of the rest of it ever worked. So I told her. Every single thing she had been doing was either the material, or the delivery of the material, or an instruction to build. Not one of them was the switch. The calcium is the brick. The D3 gets that brick out of the gut and into the blood. The K2 makes sure it goes to the bone and not the arteries. The collagen and the AlgaeCal are more of the same. More material. And the lifting, the weighted vest, the walking. Those are the order. Every heavy set she did was a message saying build here, this bone is being used. The order was arriving. The bricks were arriving. She had delivered both, every morning, for six years, faultlessly. But the stem cells had been told to make fat, not bone, and nobody had ever flipped them back. Then I told her about the drug, and why I was glad she had refused it. All the drug does is freeze the crew that clears old bone away. That is the whole of it. The worn out bone that was due to come out and be replaced just stays where it is, your number stops falling, and everybody is pleased. That is why women fracture while they are still taking it. They are holding on to old brittle bone. The switch was never flipped, no new bone was ever built to replace the old, and the moment they come off the drug it all comes down at once. In Sweden we see that rebound and we call it what it is. A fracture the treatment set up. This is the part I truly cannot get my head around about how it is done in your country. I have now explained those stem cells and that switch to every American woman who has found her way to me. And I have watched most of them go home and assemble four bottles to do it. They come back saying the same things in the same order. The energy first. Then something they had stopped doing, and they start doing it again without noticing. Then somebody in the house says it out loud before they have. And when I scan them, the number has usually gone up. Then last month one of them came in and told me something I had been waiting years to hear. She had found all four in a single formula. One bottle instead of four. Two capsules instead of eight. At the amounts the research had actually used. Rynse. NMN with the TMG, the quercetin and the trans-resveratrol. 500mg of NMN. 250mg of TMG. 150mg of quercetin. 100mg of trans-resveratrol. Not a token of one and a sprinkle of the rest. I went through all of it. The references. The formulation. Every milligram printed on the label instead of hidden inside a blend. And I checked every amount against the research I had been reading for years. They matched. All four. Somebody had read the same work I had and built the thing I had been telling women to put together themselves. Third party tested. Made in small batches. A 180 day money back guarantee, which is exactly how long a scan needs. In one study I kept returning to, postmenopausal women given NMN at this dose for twelve months showed a 12.4 percent increase in lumbar spine bone mineral density. The women given nothing kept losing it. I spent that week ringing the patients still buying four bottles at a time, to tell them they no longer had to. Now I want to say two things to you directly, as a doctor who was trained to treat this differently from the start. The first is that if you refused the drug, or if you are sitting on a prescription you have not filled, you were not being difficult. You asked what it does before you swallowed it. That is the only sensible question there is. The second is that I am genuinely sorry for how this has been handled where you live. Not by you. By a system that hands over a prescription that freezes old bone and calls a flat number a success, while the switch that builds new bone sits quietly off. The side effects on these drugs are real. The fractures that happen on them are real. The rebound when you come off is real. None of that is rare, and none of it was ever hidden. It was simply never read out to you. And here is what was never read out to you either. Holding is not building. A number that has not moved is not the same as bone that has been replaced. And the bone you are holding is getting older and more brittle every day you hold it. That is not a side effect. That is what the drug is designed to do. And most women have no idea before they fill it. You do not have to be one of them. Your bones are not thinning because you were careless. Your calcium was never wrong. Your D3 and your K2 were never wrong. Your lifting was never wrong. Every one of those was either a brick or an order to build, and neither was ever the problem. The switch that tells your stem cells to build bone instead of fat went quiet years ago, and nobody has ever turned it back on. And please do not go and buy a plain bottle of NMN off Amazon. Flipping the switch is one job out of four. I have watched women spend six months on NMN alone and come back to a number that had still gone down, because the other three jobs were never being done. Rynse was the one my patient found with all four, at the amounts the research used, in a form that actually reaches the cell. I say that after watching women fumble with four separate bottles for years. There is a 180 day money back guarantee. If your next scan has not moved, you get every cent back. They are willing to be judged by the same scan your doctor is. And if you are already on something, do not stop it on your own. Some of these are genuinely dangerous to come off without a plan, and that conversation belongs to you and your doctor. Add this alongside what you are taking, tell them you have, and ask to be scanned in six months instead of twelve. I will link it here for anyone who wants it. P.S. I have no affiliation with Rynse. I am not paid to say any of this. I say it because I have sat across from too many American women holding a scan that flatlined for years, and a prescription nobody ever explained, and I keep thinking the same thing. This did not have to happen to you. Where I trained, we ask why the bone is thinning before we reach for anything. And the answer, once you see it, is so much simpler than the drug they tried to put you on. It is now the first thing I explain to every woman who finds her way to me, instead of handing her a prescription and saying goodbye.

Engagement over time

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